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Merck

CNR1

cannabinoid receptor 1 (brain)

Synonyme:
CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1268) Summary: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]
  • Mouse(12801) cannabinoid receptor 1 (brain)
  • Rat(25248) cannabinoid receptor 1 (brain)
  • Zebrafish(404209) cannabinoid receptor 1
  • domestic cat(493926) cannabinoid receptor 1 (brain)
  • cow(100299449) cannabinoid receptor 1 (brain)
  • Horse(100065681) cannabinoid receptor 1 (brain)
  • dog(481913) cannabinoid receptor 1 (brain)
  • chicken(428633) cannabinoid receptor 1 (brain)
  • naked mole-rat(101697935) cannabinoid receptor 1 (brain)
  • domestic guinea pig(100169690) cannabinoid receptor 1 (brain)
  • sheep(101111639) cannabinoid receptor 1 (brain)

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Arachidonylethanolamide, ≥97.0% (TLC), oil,
Spezies
rat
(R)-(+)-WIN 55,212-2 -mesylat (Salz), ≥98% (HPLC),
Spezies
human
Arachidonyl-2′-chloroethylamide hydrate, ≥97% (HPLC), oil,
Spezies
rat, mouse
L-Thyroxin, ≥98% (HPLC),
Spezies
human, mouse, rat
L-Thyroxin, powder, BioReagent, suitable for cell culture,
Spezies
human, mouse, rat

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Cannabidiol -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Cannabidiol -Lösung, ~10 mg/mL in ethanol, analytical standard, for drug analysis,
Spezies
human
Cannabidiol -Lösung, 1.0 mg/mL in methanol, analytical standard, for drug analysis,
Spezies
human, rat

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Rimonabant hydrochloride, ≥98% (HPLC),
Spezies
human
Stearoyl ethanolamide, ≥98%, crystalline,
Spezies
rat
AM281, ≥98% (HPLC),
Spezies
rat
L-Thyroxin Natriumsalz Pentahydrat, γ-irradiated, powder, BioXtra, suitable for cell culture,
Spezies
mouse, rat
L-Thyroxin Natriumsalz Pentahydrat, ≥98% (HPLC), powder,
Spezies
mouse, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CNR1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cannabinoid receptor 1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
rat
Anwendung
ELISA
western blot
Anti-Cannabinoid-Rezeptor-1-Antikörper, Chemicon®, from rabbit,
Speziesreaktivität
human, monkey, rat
Anwendung
immunocytochemistry
immunohistochemistry
Anti-Cannabinoid Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Speziesreaktivität
mouse, rat
Anwendung
ELISA
western blot
Anti-CNR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
CP-55940, >98% (HPLC), powder,
Spezies
human, rat
Palmitoylethanolamide, ,
Spezies
human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cnr1,
Spezies
mouse
MISSION® esiRNA, targeting human CNR1,
Spezies
human