CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
Synonyme:
Spezies:
Human CHRNA2 (1135), Mouse Chrna2 (110902), Rat Chrna2 (170945), chicken CHRNA2 (395607), cow CHRNA2 (531838), domestic cat CHRNA2 (101092104), dog CHRNA2 (486101), sheep CHRNA2 (101107330), domestic guinea pig Chrna2 (100734964), naked mole-rat Chrna2 (101714975)
UniProtKB-ID:
Gen-ID:
- Human(1135) Summary: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009]
- Mouse(110902) cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
- Rat(170945) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- chicken(395607) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- cow(531838) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic cat(101092104) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- dog(486101) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- sheep(101107330) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- domestic guinea pig(100734964) cholinergic receptor, nicotinic, alpha 2 (neuronal)
- naked mole-rat(101714975) cholinergic receptor, nicotinic, alpha 2 (neuronal)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Produktnummer
Beschreibung
Spezies
(−)-Nikotin -Lösung, 1.0 mg/mL, analytical standard, for drug analysis,
Spezies
human, mouse, rat
Small Molecule - Antagonist
Produktnummer
Beschreibung
Spezies
(−)-Nikotin -Lösung, 1.0 mg/mL, analytical standard, for drug analysis,
Spezies
human, mouse, rat
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CHRNA2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-CHRNA2 Antibody, clone 5B2.1, clone 5B2.1, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-Chrna2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
Small Molecule - Blocker
Small Molecule - Inhibitor
Small Molecule - Ligand
esiRNA
Produktnummer
Beschreibung
Spezies