SAB5700346

Anti-Phospho-ACACA-S79 antibody produced in rabbit

• Sinónimos: ACAC, ACACA, ACACAD, ACC, ACC1, ACCA
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 257; 259; 265; 269
• species reactivity: human, rat, mouse
• concentration: 1.61 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q13085
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer79)
• Gene Information: human ... ACACA(31)

Descripción

General description

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S79 of human ACACA

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable