SAB5700327

Anti-Phospho-mTOR-S2448 antibody produced in rabbit

• Sinónimos: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1, SKS, mTOR
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 288
• species reactivity: human, mouse, rat
• concentration: 0.88 mg/ml
• technique(s): immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt accession no.: P42345
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer2448)
• Gene Information: human ... mTOR(2475)

Descripción

General description

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Immunogen

A synthetic phosphorylated peptide around S2448 of human mTOR (NP_004949.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable