SAB4300167

Anti-phospho-CDKN1B (pThr¹⁸⁷) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CDKN4 antibody produced in rabbit, Anti-KIP1 antibody produced in rabbit, Anti-MEN1B antibody produced in rabbit, Anti-MEN4 antibody produced in rabbit, Anti-cyclin-dependent kinase inhibitor 1B (p27, Kip1) antibody produced in rabbit
• MDL number: MFCD00284080
• UNSPSC Code: 12352203
• NACRES: NA.43

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~27 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (E-Q-TP-P-K)
• NCBI accession no.: NP_004055.1
• UniProt accession no.: P46527
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr187)
• Gene Information: human ... CDKN1B(1027)

Descripción

Immunogen

Peptide sequence around phosphorylation site of threonine 187 (E-Q-T(p)-P-K), according to the protein CDKN1B.

Features and Benefits

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Target description

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable