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Key Documents

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I6891

Sigma-Aldrich

H-7

Sinónimos:

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide

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About This Item

Fórmula empírica (notación de Hill):
C14H17N3O2S
Número de CAS:
84477-87-2
Peso molecular:
291.37
Beilstein/REAXYS Number:
5482740
MDL number:
MFCD00063403
UNSPSC Code:
12352200
PubChem Substance ID:
24896097
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

mp

114 °C

solubility

ethanol: 20 mg/mL
1 M HCl: 5 mg/mL

storage temp.

2-8°C

SMILES string

CC1CNCCN1S(=O)(=O)c2cccc3cnccc23

InChI

1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3

InChI key

BDVFVCGFMNCYPV-UHFFFAOYSA-N

Gene Information

human ... CALCRL(10203)
rat ... Calcrl(25029)

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Biochem/physiol Actions

Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Molecules (Basel, Switzerland), 24(20) (2019-10-24)
Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-c:5,6-c']difuro[2,3-c:4,5-c']-diquinoline-6,14(5H,12H)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[d]oxazol-2-yl)-3-hydroxy-1H-[4,5]oxazolo[3,2-a]pyridine-1-one. The new candidates were synthesized and identified by different spectroscopic techniques, and X-ray crystallography.
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