G1278

Galantide

≥90% (HPLC)

• Sinónimos: M15
• Fórmula empírica (notación de Hill): C₁₀₄H₁₅₁N₂₅O₂₆S
• Número de CAS: 138579-66-5
• Peso molecular: 2199.53
• MDL number: MFCD00144384
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799835
• NACRES: NA.26

Propiedades

• assay: ≥90% (HPLC)
• form: powder
• technique(s): drug transporter assay: suitable
• color: white
• UniProt accession no.: P22466
• storage temp.: −20°C
• SMILES string: CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]3CCCN3C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc5c[nH]c6ccccc56)NC(=O)CN)[C@@H](C)O)C(N)=O
• InChI: 1S/C104H151N25O26S/c1-54(2)39-70(91(142)113-52-87(139)129-37-20-27-80(129)103(154)120-69(33-35-82(107)134)93(144)119-68(32-34-81(106)133)94(145)124-76(44-61-23-16-13-17-24-61)99(150)123-74(43-60-21-14-12-15-22-60)92(143)112-51-86(138)116-71(40-55(3)4)95(146)118-67(89(109)140)36-38-156-11)121-96(147)72(41-56(5)6)122-98(149)75(45-62-28-30-64(132)31-29-62)117-85(137)50-111-90(141)58(9)114-102(153)79(53-130)127-100(151)78(47-83(108)135)125-97(148)73(42-57(7)8)126-104(155)88(59(10)131)128-101(152)77(115-84(136)48-105)46-63-49-110-66-26-19-18-25-65(63)66/h12-19,21-26,28-31,49,54-59,67-80,88,110,130-132H,20,27,32-48,50-53,105H2,1-11H3,(H2,106,133)(H2,107,134)(H2,108,135)(H2,109,140)(H,111,141)(H,112,143)(H,113,142)(H,114,153)(H,115,136)(H,116,138)(H,117,137)(H,118,146)(H,119,144)(H,120,154)(H,121,147)(H,122,149)(H,123,150)(H,124,145)(H,125,148)(H,126,155)(H,127,151)(H,128,152)/t58-,59+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,88-/m0/s1
• InChI key: TZOJVPDIYKRJSM-GKPUQKAJSA-N
• Gene Information: human ... GAL(51083)

Descripción

Amino Acid Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

Biochem/physiol Actions

Galanin receptor antagonist

Galanin, a neuropeptide, mediates its physiological effects through three G protein-coupled receptor (GCPR) subtypes, GalR1, GalR2, and GalR3. Galantide, C7, M35, and M40 are Galanin receptor antagonists used to differentiate and characterize Galanin receptor signaling pathways that impact processes such as acute pancreatitis.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)