CS0410
Glutathione-S-Transferase (GST) Assay Kit
sufficient for 500 multiwell tests
Sinónimos:
GST Enzyme Activity Kit
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About This Item
Productos recomendados
usage
sufficient for 500 multiwell tests
Quality Level
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... GSTA4(2941) , GSTM1(2944)
General description
The Glutathione S-Transferase (GST) Assay Kit is designed to measure total GSTactivity. It can be used to measure GST activity in cell and bacterial lysates, tissue homogenates, and in plasma
and erythrocyte lysates
and erythrocyte lysates
Application
The Glutathione S-Transferase Assay kit utilizes 1-Chloro-2,4-dinitrobenzene (CDNB), which is suitable for the broadest range of GST isozymes. Upon conjugation of the thiol group of glutathione to the CDNB substrate, there is an increase in the absorbance at 340 nm.
Biochem/physiol Actions
Glutathione S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is present in plants, insects, yeast, bacteria, and most mammalian tissues especially in the liver, which plays a key role in detoxification.
Solo componentes del kit
Referencia del producto
Descripción
- Dulbecco's Phosphate Buffered Saline 100 mL
- L-Glutathione Reduced 1 g
- GST (Control) .1 mL
- Sample Buffer 5 mL
- Substrate (CDNB) 1.2 mL
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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