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Key Documents

Y0000437

Chlorphenamine impurity C

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(3RS)-3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine

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About This Item

Fórmula empírica (notación de Hill):
C15H17ClN2
Número de CAS:
Peso molecular:
260.76
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

chlorpheniramine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C15H17ClN2/c1-17-11-9-14(15-4-2-3-10-18-15)12-5-7-13(16)8-6-12/h2-8,10,14,17H,9,11H2,1H3

InChI key

UICFCNIVUDNZSW-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorphenamine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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B T Hiep et al.
Journal of chromatography. B, Biomedical sciences and applications, 707(1-2), 235-240 (1998-06-05)
The enantiomers of chlorpheniramine and its monodesmethyl metabolite were determined separately in urine by using a coupled achiral-chiral chromatographic system. The two enantiomers of the studied compound and the internal standard were separated from the biological matrix on a cyanopropyl
K J Simons et al.
Journal of pharmaceutical sciences, 73(5), 595-599 (1984-05-01)
The pharmacokinetics and urinary excretion of chlorpheniramine were studied in 11 patients, aged 6-16 years, with allergic rhinitis. In these children, chlorpheniramine had a mean elimination half-life of 13.1 +/- 6.6 h, a mean clearance rate of 7.23 +/- 3.16
Skin permeation of chlorpheniramine maleate and detection of demethylated metabolites by high-performance liquid chromatography.
S Zbaida et al.
Journal of pharmaceutical sciences, 77(2), 188-190 (1988-02-01)

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