L0745000

Lomustine

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
• Fórmula empírica (notación de Hill): C₉H₁₆ClN₃O₂
• Número de CAS: 13010-47-4
• Peso molecular: 233.70
• MDL number: MFCD00012392
• UNSPSC Code: 41116107
• PubChem Substance ID: 329817373
• NACRES: NA.24

Propiedades

• grade: pharmaceutical primary standard
• API family: lomustine
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: ClCCN(N=O)C(=O)NC1CCCCC1
• InChI: 1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)
• InChI key: GQYIWUVLTXOXAJ-UHFFFAOYSA-N

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lomustine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 - H350
• pcodes: P201 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable