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Merck
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Documentos

81292

Supelco

Poli(etilenglicol)

analytical standard, for GPC, 4,000

Sinónimos:

PEG

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About This Item

Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24887743
NACRES:
NA.24

grade

analytical standard
for GPC

Quality Level

100

shelf life

limited shelf life, expiry date on the label

mol wt

Mn ~4120
Mp ~4450
Mw ~4240

technique(s)

gel permeation chromatography (GPC): suitable

Mw/Mn

~1.03

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) (PEG) is regarded as the gold standard for stealth polymers in polymer based drug delivery. PEGs and their anionic or non-ionic derivatives are widely used in cosmetic products.

Application

PEG is known to modify enzymes and proteins for the preparation of improved therapeutic agents.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCJ8167
BCCJ3834
BCCH9315
BCCH2607
BCCG7919

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Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products.
Fruijtier-Polloth C.
Toxicology, 214(1-2), 1-38 (2005)
C Woghiren et al.
Bioconjugate chemistry, 4(5), 314-318 (1993-09-01)
Monomethoxypolyethylene glycol (mPEG) of average molecular weight 5000 was transformed in a series of synthetic steps to a new activated form of PEG, a stable thiol-protected intermediary, for reaction with cysteine residues in proteins under mild conditions to produce PEG--protein
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Knop K, et al.
Angewandte Chemie (International Edition in English), 49(36), 6288-6308 (2010)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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