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Merck
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Key Documents

06-983

Sigma-Aldrich

Anti-GADS Antibody

Upstate®, from rabbit

Sinónimos:

Anti-GADS, Anti-GRAP-2, Anti-GRB2L, Anti-GRBLG, Anti-GRID, Anti-GRPL, Anti-GrbX, Anti-Grf40, Anti-Mona, Anti-P38

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_004810

UniProt accession no.

O75791

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GRAP2(9402)

Specificity

GADS

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 174-188 of murine GADS (GEEIRPSVNRKLSDH)

Application

Anti-GADS Antibody is an antibody against GADS for use in IP & WB.

Quality

routinely evaluated by immunoblot on Jurkat RIPA cell lysate

Target description

40kDa

Physical form

Format: Purified

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses.
Jr-Wen Shui, Jonathan S Boomer, Jin Han, Jun Xu, Gregory A Dement, Guisheng Zhou, Tse-Hua Tan
Nature Immunology null
Eri Ishikawa et al.
Nature communications, 7, 12756-12756 (2016-09-28)
Thymic selection shapes an appropriate T cell antigen receptor (TCR) repertoire during T cell development. Here, we show that a serine/threonine kinase, protein kinase D (PKD), is crucial for thymocyte positive selection. In T cell-specific PKD-deficient (PKD2/PKD3 double-deficient) mice, the
Luminal leptin inhibits L-glutamine transport in rat small intestine: involvement of ASCT2 and B0AT1.
Ducroc R, Sakar Y, Fanjul C, Barber A, Bado A, Lostao MP
American Journal of Physiology: Gastrointestinal and Liver Physiology null
Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
Roncagalli, R; Hauri, S; Fiore, F; Liang, Y; Chen, Z; Sansoni, A; Kanduri, K; Joly et al.
Nature Immunology null
Juris A Grasis et al.
Molecular and cellular biology, 30(14), 3596-3609 (2010-05-12)
In vitro data have suggested that activation of the inducible T-cell kinase (ITK) requires an interaction with the adaptor protein SLP-76. One means for this interaction involves binding of the ITK SH3 domain to the polyproline-rich (PR) region of SLP-76.

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