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Merck

850468C

Avanti

18:0-18:2 PC

1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine, chloroform

Sinónimos:

1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(18:0/18:2(9Z,12Z))

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About This Item

Fórmula empírica (notación de Hill):
C44H84NO8P
Número de CAS:
Peso molecular:
786.11
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850468C-25mg)
pkg of 2 × 4 mL (850468C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850468C

concentration

10 mg/mL (850468C-25mg)
25 mg/mL (850468C-200mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,42H,6-14,16,18-20,22,24-41H2,1-5H3/b17-15-,23-21-/t42-/m1/s1

InChI key

FORFDCPQKJHEBF-VPUSDGANSA-N

General description

18:0-18:2 PC is a non-fragmented oxidized phosphotidylcholine. It is a component of low density lipoprotein (LDL), which is a polyunsaturated fatty acid.

Application

18:0-18:2 PC may be used to study the effect of phospholipids on lubrication of damaged mesothelium of lungs. It has been used for the preparation of liposomes.

Packaging

5 mL Clear Glass Sealed Ampule (850468C-200mg)
5 mL Clear Glass Sealed Ampule (850468C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Lubricating recovery of damaged pleural mesothelium: effect of time and of phosphatidylcholines
Bodega F, et al.
Respiratory Physiology & Neurobiology, 203(2), 116-120 (2014)
Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury
Solati Z, et al.
PLoS ONE, 13(4), e0195172-e0195172 (2018)
Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
Rynkiewicz M J, et al.
Biochemistry, 56(31), 4095-4105 (2017)
Ginger L Milne et al.
Journal of lipid research, 46(2), 307-319 (2004-11-18)
Phospholipids reside in the surface layer of LDLs and constitute approximately 20-25% of the particle by weight. We report a study of the primary products generated from the most abundant molecular species of phosphatidylcholines present in LDL during in vitro
Wenbo Cao et al.
Analytical chemistry, 90(17), 10286-10292 (2018-08-11)
The presence of carbon-carbon double bonds (C═Cs) in unsaturated phospholipids is closely related to lipid conformations and physiochemical activities. Previously, we have demonstrated that epoxidation reaction facilitated by low-temperature plasma (LTP) enabled the structural analysis of unsaturated fatty acids (FAs).

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