850469C

18:0-20:4 PC

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, chloroform

• Sinónimos: 1-octadecanoyl-2-arachidonyl-sn-glycero-3-phosphocholine; SAPC; PC(18:0/20:4(5Z,8Z,11Z,14Z))
• Fórmula empírica (notación de Hill): C₄₆H₈₄NO₈P
• Número de CAS: 35418-59-8
• Peso molecular: 810.13
• MDL number: MFCD00082436
• UNSPSC Code: 51191904
• NACRES: NA.25

Propiedades

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (850469C-25mg); pkg of 2 × 4 mL (850469C-200mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850469C
• concentration: 10 mg/mL (850469C-25mg); 25 mg/mL (850469C-200mg)
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C46H84NO8P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-39-46(49)55-44(43-54-56(50,51)53-41-40-47(3,4)5)42-52-45(48)38-36-34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h14,16,20,22,25,27,31,33,44H,6-13,15,17-19,21,23-24,26,28-30,32,34-43H2,1-5H3/b16-14-,22-20-,27-25-,33-31-/t44-/m1/s1
• InChI key: PSVRFUPOQYJOOZ-QNPWAGBNSA-N

Descripción

General description

18:0-20:4 Phosphatidylcholine (PC) has saturated (18:0) chain in the sn-1 position and unsaturated (20:4) in the sn-2 position. Asymmetric combinations of PC is common among mammalian lipids. PC is a zwitterionic phospholipid. PC is synthesized by Kennedy pathway from choline.

Application

18:0-20:4 PC is suitable for use:

• in the preparation of liposomes
• in the synthesis of diacylglycerol
• as substrate to determine the activity of phospholipase A2 (PLA2)

Biochem/physiol Actions

18:0-20:4 phosphatidylcholine (PC) is more prominent in specialized membranes like synaptic vesicles. Phosphatidylcholine is one of the major glycerophospholipids of the eukaryotic membranes. It is essential for maintaining the structure and functions of the membrane. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol.

Packaging

5 mL Clear Glass Sealed Ampule (850469C-200mg)

5 mL Clear Glass Sealed Ampule (850469C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash