538507

2-Amino-6-bromobenzothiazole

97%

• Fórmula empírica (notación de Hill): C₇H₅BrN₂S
• Número de CAS: 15864-32-1
• Peso molecular: 229.10
• MDL number: MFCD00152229
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878338
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 97%
• form: solid
• mp: 213-217 °C (lit.)
• SMILES string: Nc1nc2ccc(Br)cc2s1
• InChI: 1S/C7H5BrN2S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H2,9,10)
• InChI key: VZEBSJIOUMDNLY-UHFFFAOYSA-N

Descripción

General description

Reaction of 4-bromoaniline with acetic acid and potassium thiocynate in solution of bromine in acetic acid yields 2-amino-6-bromobenzothiazole. 2-Amino-6-bromobenzothiazole can also be synthesized from 2-aminobenzothiazole via monobromination with silica-supported quinolinium tribromide.

Application

2-Amino-6-bromobenzothiazole may be used in the synthesis of the following

• 2-amino-6-arylbenzothiazole compounds:
• 6-p-tolylbenzo[d]thiazole-2-amine
• 6-(4chlorophenyl)benzo[d]thiazole-2-amine
• 6-(4-methoxyphenyl)benzo[d]thiazole-2-amine
• 6-(3,5-bis(triflouromethyl)phenyl)benzo[d]thiazole-2-amine
• 6-phenylbenzo[d]thiazole-2-amine

It may be employed as a ligand (L) in the synthesis of organometallic derivatives of Rh(I) [Rh(CO)₂(L)(Cl)].

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves