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Key Documents

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47628

Sigma-Aldrich

Fmoc-Ile-OH

≥98.0% (T)

Sinónimos:

N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine, Fmoc-L-isoleucine

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About This Item

Fórmula empírica (notación de Hill):
C21H23NO4
Número de CAS:
71989-23-6
Peso molecular:
353.41
Beilstein/REAXYS Number:
4716717
EC Number:
276-255-9
MDL number:
MFCD00037125
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57651048
NACRES:
NA.26

Quality Level

100

assay

≥98.0% (T)

form

solid

optical activity

[α]20/D −12±1°, c = 1% in DMF

reaction suitability

reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis

mp

145-147 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc
amine
carboxylic acid

storage temp.

2-8°C

SMILES string

CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

InChI key

QXVFEIPAZSXRGM-DJJJIMSYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCD7459
BCCD7457
BCCD5472
BCBZ6720
BCBT4068

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Moise Ndao et al.
Langmuir : the ACS journal of surfaces and colloids, 34(29), 8678-8684 (2016-04-05)
Diatoms are unicellular algae that construct cell walls called frustules by the precipitation of silica, using special proteins that order the silica into a wide variety of nanostructures. The diatom species Cylindrotheca fusiformis contains proteins called silaffins within its frustules
Karthik Nadendla et al.
Molecular pharmaceutics, 16(7), 2922-2928 (2019-05-24)
We have previously described the photoactivated depot (PAD) approach for the light-stimulated release of therapeutic proteins such as insulin. The aim of this method is to release insulin from a shallow dermal depot in response to blood glucose information, using
R Ashton Lavoie et al.
International journal of molecular sciences, 20(7) (2019-04-11)
The growing integration of quality-by-design (QbD) concepts in biomanufacturing calls for a detailed and quantitative knowledge of the profile of impurities and their impact on the product safety and efficacy. Particularly valuable is the determination of the residual level of
R Ashton Lavoie et al.
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
K R Sunil Kumar et al.
ACS nano, 8(5), 4157-4165 (2014-04-01)
To apply motor proteins as natural nanomolecular machines to transporting systems in nanotechnology, complete temporal control over ON/OFF switching of the motility is necessary. We have studied the photoresponsive inhibition properties of azobenzene-tethered peptides for regulation of kinesin-microtubule motility. Although
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