367532
5-Chloro-1-methyl-4-nitroimidazole
98%
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Fórmula empírica (notación de Hill):
C4H4ClN3O2
Número de CAS:
Peso molecular:
161.55
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Productos recomendados
Quality Level
assay
98%
mp
148-150 °C (lit.)
functional group
chloro
nitro
SMILES string
Cn1cnc(c1Cl)[N+]([O-])=O
InChI
1S/C4H4ClN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3
InChI key
OSJUNMSWBBOTQU-UHFFFAOYSA-N
¿Está buscando productos similares? Visita Guía de comparación de productos
General description
5-Chloro-1-methyl-4-nitroimidazole is an 4-nitroimidazole derivative.
Application
5-Chloro-1-methyl-4-nitroimidazole (CMNI) is suitable for use in the rapid mix experiments to investigate the mechanism of anomalous radiosensitization of mammalian cells by CMNI. It may be used in the synthesis of 5-aryl-1-methyl-4-nitroimidazoles, via Suzuki coupling with arylboronic acids, catalyzed by dichlorobis-(triphenylphosphine)palladium(II), K2CO3 and tetrabutylammonium bromide.
Related product
Referencia del producto
Descripción
Precios
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Rapid-mix studies on the anomalous radiosensitization of mammalian cells by 5-chloro-1-methyl-4-nitromidazole.
M E Watts et al.
International journal of radiation biology and related studies in physics, chemistry, and medicine, 38(6), 673-675 (1980-12-01)
M E Watts et al.
International journal of radiation oncology, biology, physics, 12(7), 1135-1138 (1986-07-01)
The "extra" radiosensitization seen with GSH-reactive nitro compounds is too large to be accounted for by GSH-depletion acting independently--there must be competition. The GS-conjugate leaks out of cells slowly and is trapped at high concentrations. Its properties, such as concentration
The effect of electron-affinic radiosensitizers on ATP levels in V79 379A Chinese hamster cells.
R J Hodgkiss
Biochemical pharmacology, 36(3), 393-396 (1987-02-01)
The kinetics of the reaction of 'anomalous' 4-nitroimidazole radiosensitizers with thiols.
P Wardman
International journal of radiation biology and related studies in physics, chemistry, and medicine, 41(2), 231-235 (1982-02-01)
Occupational allergic contact dermatitis from 5-chloro-1-methyl-4-nitroimidazole.
R Jolanki et al.
Contact dermatitis, 36(1), 53-54 (1997-01-01)
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico