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Merck

177466

Sigma-Aldrich

4-Methylcyclohexylamine, mixture of cis and trans

97%

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About This Item

Fórmula lineal:
CH3C6H10NH2
Número de CAS:
Peso molecular:
113.20
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

form

liquid

refractive index

n20/D 1.4531 (lit.)

bp

151-154 °C (lit.)

density

0.855 g/mL at 25 °C (lit.)

SMILES string

CC1CCC(N)CC1

InChI

1S/C7H15N/c1-6-2-4-7(8)5-3-6/h6-7H,2-5,8H2,1H3

InChI key

KSMVBYPXNKCPAJ-UHFFFAOYSA-N

General description

Trans-4-methylcyclohexylamine is a spermidine synthase inhibitor.

pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

80.6 °F - closed cup

flash_point_c

27 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Masatake Sano et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 845(1), 80-83 (2006-08-26)
An assay for spermidine synthase (SPDS) activity in rat liver has been developed using micellar electrokinetic chromatography (MEKC) with laser-induced fluorescence (LIF) detection to enable the discovery of SPDS inhibitors. The assay was established by estimating the amount of spermidine
Trans-4-methylcyclohexylamine, a potent new inhibitor of spermidine synthase.
A Shirahata et al.
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Biological & pharmaceutical bulletin, 28(4), 569-573 (2005-04-02)
In rat tissues, a decrease in spermidine, accompanied by an increase in spermine was induced by the oral administration (once daily for either 1 week or 1 month) of trans-4-methylcyclohexylamine (4MCHA), a spermidine synthase inhibitor. This is similar to the

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