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Merck
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Documentos

141712

Sigma-Aldrich

trans-1,2-Cyclohexanediol

98%

Sinónimos:

1,2-trans -Cyclohexanediol, 1,2-trans -Dihydroxycyclohexane, trans -2-Hydroxycyclohexanol

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About This Item

Fórmula lineal:
C6H10(OH)2
Número de CAS:
1460-57-7
Peso molecular:
116.16
Beilstein/REAXYS Number:
3193810
EC Number:
215-956-6
MDL number:
MFCD00063611
UNSPSC Code:
12162002
PubChem Substance ID:
24848511
NACRES:
NA.23

assay

98%

form

solid

mp

101-104 °C (lit.)

SMILES string

O[C@@H]1CCCC[C@H]1O

InChI

1S/C6H12O2/c7-5-3-1-2-4-6(5)8/h5-8H,1-4H2/t5-,6-/m1/s1

InChI key

PFURGBBHAOXLIO-PHDIDXHHSA-N

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Lisa D Cervia et al.
Molecular therapy. Nucleic acids, 11, 263-271 (2018-06-03)
The nuclear envelope is a physiological barrier to electrogene transfer. To understand different mechanisms of the nuclear entry for electrotransfected plasmid DNA (pDNA), the current study investigated how manipulation of the mechanisms could affect electrotransfection efficiency (eTE), transgene expression level
Sigthor Petursson
Carbohydrate research, 338(9), 963-968 (2003-04-12)
The paper reports the tin(II) chloride catalyzed reactions of diazodiphenylmethane with the cis- and trans-1,2-cyclohexanediols and R,S-1,2-propanediol in 1,2-dimethoxyethane and the identification of the monodiphenylmethyl ethers formed. The catalyst is shown to work for both the cis- and trans-cyclohexanediols, but
T Kiguchi et al.
Chemical & pharmaceutical bulletin, 48(10), 1536-1540 (2000-10-25)
Asymmetric spirocyclization based on intramolecular conjugate addition using a combination of a Lewis acid and an optically active cyclohexane-1,2-diol has been studied in connection with 1) the effect of substituents on the cyclohexane-1,2-diol and 2) the effect of substituents on
Ivan Liashkovich et al.
Journal of controlled release : official journal of the Controlled Release Society, 160(3), 601-608 (2012-03-06)
The efficiency of gene therapy in non-dividing cells is particularly poor due to restricted nuclear delivery rates of exogenously applied macromolecules across the nuclear pore complexes (NPCs). Therefore, improved intranuclear delivery of transgenes requires an ability to modulate the barrier
Ine Lentacker et al.
Journal of controlled release : official journal of the Controlled Release Society, 132(3), 279-288 (2008-07-29)
After administration to the body, nucleic acid containing nanoparticles (NANs) need to cross several extra- and intracellular barriers to reach the cytoplasm or nucleus of the target cells. In the last decade several groups tried to overcome these barriers by
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