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PTPRA

protein tyrosine phosphatase, receptor type, A

Synonyms:
HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
Species:
UniProtKB ID:
Gene ID:
  • Human(5786) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19262) protein tyrosine phosphatase, receptor type, A
  • Rat(25167) protein tyrosine phosphatase, receptor type, A
  • Zebrafish(140818) protein tyrosine phosphatase, receptor type, A
  • Horse(100066880) protein tyrosine phosphatase, receptor type, A
  • domestic cat(101096558) protein tyrosine phosphatase, receptor type, A
  • dog(477176) protein tyrosine phosphatase, receptor type, A
  • chicken(396060) protein tyrosine phosphatase, receptor type, A
  • cow(100138017) protein tyrosine phosphatase, receptor type, A
  • sheep(101101909) protein tyrosine phosphatase, receptor type, A
  • naked mole-rat(101716097) protein tyrosine phosphatase, receptor type, A
  • Domestic Rabbit(100342875) protein tyrosine phosphatase, receptor type, A
  • domestic guinea pig(100720460) protein tyrosine phosphatase, receptor type, A

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-phospho-PTPRA (pTyr798) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-PTPRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PTPRA antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-Phospho-PTPRA-Y789 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Milrinone, ≥97% (TLC), powder,
Species
rat, human

Proteins

Product Number
Description
Species
PTPRA (174-802), active, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTPRA, VPS16,
Species
human
MISSION® esiRNA, targeting mouse Ptpra,
Species
mouse