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BPGM

2,3-bisphosphoglycerate mutase

Synonyms:
DPGM
Species:
UniProtKB ID:
Gene ID:
  • Human(669) Summary: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
  • Mouse(12183) 2,3-bisphosphoglycerate mutase
  • Rat(296973) 2,3-bisphosphoglycerate mutase
  • Zebrafish(436903) 2,3-bisphosphoglycerate mutase
  • dog(482704) 2,3-bisphosphoglycerate mutase
  • domestic cat(101095644) 2,3-bisphosphoglycerate mutase
  • cow(533785) 2,3-bisphosphoglycerate mutase
  • chicken(418172) 2,3-bisphosphoglycerate mutase
  • domestic guinea pig(100722842) 2,3-bisphosphoglycerate mutase
  • naked mole-rat(101706859) 2,3-bisphosphoglycerate mutase
  • sheep(101121089) 2,3-bisphosphoglycerate mutase
  • Domestic Rabbit(100009096) 2,3-bisphosphoglycerate mutase

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-BPGM (ab2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BPGM,
Species
human
MISSION® esiRNA, targeting mouse Bpgm,
Species
mouse