1000818

Abiraterone acetate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 17-(Pyridin-3-yl)androsta-5,16-dien-3β-yl acetate
• Empirical Formula (Hill Notation): C₂₆H₃₃NO₂
• CAS Number: 154229-18-2
• Molecular Weight: 391.55
• MDL number: MFCD00934213
• UNSPSC Code: 41116107
• PubChem Substance ID: 329748877
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: abiraterone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: C[C@]12C(C[C@@H](OC(C)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC=C4C5=CC=CN=C5
• InChI: 1S/C26H33NO2/c1-17(28)29-20-10-12-25(2)19(15-20)6-7-21-23-9-8-22(18-5-4-14-27-16-18)26(23,3)13-11-24(21)25/h4-6,8,14,16,20-21,23-24H,7,9-13,15H2,1-3H3/t20-,21-,23-,24-,25-,26+/m0/s1
• InChI key: UVIQSJCZCSLXRZ-UBUQANBQSA-N
• Gene Information: human ... CYP17A1(1586)

Description

General description

Abiraterone acetate is a pro-drug of abiraterone and a potent inhibitor of the enzyme CYP17, required for androgen biosynthesis in the adrenal glands, testes and prostate tissue.

Application

Abiraterone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Abiraterone Acetate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H360F,H373,H410
• Precautionary Statements: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Chronic 1 - Repr. 1B - STOT RE 2
• Target Organs: Endocrine system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable