Skip to Content
Merck
All Photos(1)

Key Documents

SML3564

Sigma-Aldrich

ML382

≥98% (HPLC)

Synonym(s):

VU0485891, 2-(Cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C18H20N2O4S
CAS Number:
Molecular Weight:
360.43
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Pricing and availability is not currently available.

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1=C(C=CC=C1)NS(C2CC2)(=O)=O)NC3=C(C=CC=C3)OCC

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SML1920SML3261SML1639
ML382 ≥98% (HPLC)

SML3564

ML382

Sigma-Aldrich

SML1920

ML364

JS6 ≥98% (HPLC)

SML3261

JS6

BRD3308 ≥98% (HPLC)

SML1639

BRD3308

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige

Biochem/physiol Actions

ML382 is a positive allosteric modulator of Mas-related G-protein-coupled receptor X1 (MrgprX1, MrgX1, SNSR4), a G-protein coupled receptor (GPCR) selectively expressed in dorsal root ganglion (DRG) neurons. MrgX1 is believed to be a functional ortholog of mouse MrgC11, which has been shown to be involved in itch and pain. ML382 is selective for MrgX1 over MrgX2, MrgC11 and a panel of 68 other GPCRs, ion channels and transporters, with an EC50 value of 190 nm with an Emax value of 148% in the presence of the known ligand BAM8-22.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


  • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service