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Key Documents

SAE0153

Sigma-Aldrich

Leupeptin Ready Made Solution

Non-freezing solution, 5 mg/ml

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.54

biological source

microbial

Quality Level

Assay

≥90% (HPLC)

form

ready-to-use solution

concentration

5 mg/mL

storage temp.

−20°C

General description

Leupeptin is a tripeptide protease inhibitor that is naturally produced in Actinomyces / Streptomyces. Known also as N-acetyl-L-leucyl-L-leucyl-L-arginal, leupeptin is a reversible competitive inhibitor of cysteine, serine, and thiol proteases.

Features and Benefits

  • Inhibitor of serine and cysteine proteases
  • Inhibits plasmin, trypsin, papain, calpain, and cathepsin B
  • Does not inhibit pepsin, cathepsin A, cathepsin D, thrombin, or α-chymotrypsin
  • Effective concentration: 10 μM - 100 μM
  • Convenient 5 mM non-freezing solution, ready to dilute to the desired working concentration

Storage Class Code

10 - Combustible liquids

WGK

WGK 2


Certificates of Analysis (COA)

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