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P5069

Sigma-Aldrich

Prostaglandin F2α tris salt

synthetic, suitable for cell culture

Synonym(s):

(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF2α−Tris

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About This Item

Empirical Formula (Hill Notation):
C20H34O5 · C4H11NO3
CAS Number:
38562-01-5
Molecular Weight:
475.62
Beilstein:
4087514
EC Number:
254-002-3
MDL number:
MFCD00077863
UNSPSC Code:
12352209
PubChem Substance ID:
24898587
NACRES:
NA.77
biological source:
synthetic
form:
powder
Pricing and availability is not currently available.

biological source

synthetic

Quality Level

200

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

ethanol: 50 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC

InChI

1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1

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1 of 4

This Item
P0424P7527P0409
Prostaglandin F2α tris salt synthetic, suitable for cell culture

P5069

Prostaglandin F2α tris salt

Prostaglandin F2α tris salt ≥99%, synthetic, powder

P0424

Prostaglandin F2α tris salt

Prostaglandin E1 γ-irradiated, powder, BioXtra, suitable for cell culture

P7527

Prostaglandin E1

Prostaglandin E2 synthetic, powder, BioReagent, suitable for cell culture

P0409

Prostaglandin E2

assay

≥99%

assay

≥99%

assay

≥60% (HPLC)

assay

≥93% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

form

powder

form

powder

form

powder

form

powder

shipped in

ambient

shipped in

ambient

shipped in

-

shipped in

ambient

Biochem/physiol Actions

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds.
Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F2α and luteal oxytocin is responsible for completion of luteolysis.
Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.
Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H360FD

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLBZ4588
    SLBW6336
    SLBR1962V
    SLBK9406V
    029K3784

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    Kurt J Sales et al.
    Biochimica et biophysica acta, 1793(12), 1917-1928 (2009-10-13)
    Pro-inflammatory mediators, like prostaglandin (PG) and chemokines, promote tumourigenesis by enhancing cell proliferation, migration of immune cells and recruitment of blood vessels. Recently we showed elevated expression of the chemokine (C-X-C motif) receptor 2 (CXCR2) in endometrial adenocarcinomas localized to
    Matthew Elmes et al.
    Physiological reports, 3(4) (2015-04-17)
    Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section. We investigated the influence of maternal age on myometrial contractility, expression of contractile associated proteins (CAPs), and global
    Augusta Zannoni et al.
    Reproductive biology and endocrinology : RB&E, 5, 31-31 (2007-07-31)
    The corpus luteum (CL) is a transient endocrine gland and prostaglandin F2-alpha is considered to be the principal luteolysin in pigs. In this species, the in vivo administration of prostaglandin F2-alpha induces apoptosis in large vessels as early as 6
    Jeffrey R Sommer et al.
    Animal reproduction science, 100(3-4), 402-410 (2006-11-23)
    An efficient protocol was developed to synchronize and superovulate mature pigs for the collection of pronuclear stage embryos suitable for DNA microinjection. A timed and coordinated regimen of Lutalyse, PG600 and Chorulon along with daily checking for estrus allowed synchronization
    G J Nie et al.
    American journal of veterinary research, 62(8), 1285-1289 (2001-08-11)
    To determine whether administration of a microdose of prostaglandin at the BAI HUI acupuncture point offers any advantage over IM injections for luteolysis, ovulatory interval, or systemic response in mares. 17 mature cycling mares, 3 to 20 years of age
    View All Related Papers

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