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Key Documents

M6546

Sigma-Aldrich

(±)-2-(p-Methoxyphenoxy)propionic acid

solid, ≥98%

Synonym(s):

PMP

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About This Item

Empirical Formula (Hill Notation):
C10H12O4
CAS Number:
Molecular Weight:
196.20
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

product name

(±)-2-(p-Methoxyphenoxy)propionic acid, ≥98%

biological source

synthetic (organic)

Quality Level

Assay

≥98%

form

solid

SMILES string

COc1ccc(OC(C)C(O)=O)cc1

InChI

1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

InChI key

MIEKOFWWHVOKQX-UHFFFAOYSA-N

Application

(±)-2-(p-Methoxyphenoxy)propionic acid may be used as a sweet taste receptor antagonist to study its effect on allulose-induced glucagon-like peptide 1 (GLP-1) secretion rats. It may also be used to study the response of the secretin tumor cell line (STC-1) to sweetener in the presence and absence of (±)-2-(p-methoxyphenoxy)propionic acid or lactisole.

Biochem/physiol Actions

As a taste modulator, the sodium salt inhibits the perception of sweetness in humans, but not in rats.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Physiology & behavior, 61(1), 25-29 (1997-01-01)
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