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Key Documents

M0895

Sigma-Aldrich

MES potassium salt

≥99% (titration)

Synonym(s):

2-(N-Morpholino)ethanesulfonic acid potassium salt, 4-Morpholineethanesulfonic acid potassium salt

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About This Item

Empirical Formula (Hill Notation):
C6H12KNO4S
CAS Number:
Molecular Weight:
233.33
MDL number:
UNSPSC Code:
12161700
eCl@ss:
32129211
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99% (titration)

form

crystalline powder

useful pH range

5.5-6.7

pKa 

6.1

solubility

water: 0.33 g/mL, clear, colorless

SMILES string

[K+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.K/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

InChI key

IMFIKFZWLAWMQE-UHFFFAOYSA-M

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Application

MES potassium salt has been used as a component of buffers for the preparation of permeabilized fiber bundles.

Biochem/physiol Actions

MES is applicable as a Good′s buffer and is widely used in regulating the pH of reagent solutions, physiological experiments and plant culture medium.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ashley S Williams et al.
Cell metabolism, 31(1), 131-147 (2019-12-10)
This study sought to examine the functional significance of mitochondrial protein acetylation using a double knockout (DKO) mouse model harboring muscle-specific deficits in acetyl-CoA buffering and lysine deacetylation, due to genetic ablation of carnitine acetyltransferase and Sirtuin 3, respectively. DKO
Trace Thome et al.
American journal of physiology. Cell physiology, 317(4), C701-C713 (2019-07-11)
Chronic kidney disease (CKD) leads to increased skeletal muscle fatigue, weakness, and atrophy. Previous work has implicated mitochondria within the skeletal muscle as a mediator of muscle dysfunction in CKD; however, the mechanisms underlying mitochondrial dysfunction in CKD are not

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