L1292

Latanoprost acid

≥95% (HPLC)

• Synonym(s): (5Z,9α,11α,15R)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oic acid, (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid, PhXA 85
• Empirical Formula (Hill Notation): C₂₃H₃₄O₅
• CAS Number: 41639-83-2
• Molecular Weight: 390.51
• MDL number: MFCD08056084
• UNSPSC Code: 12352106
• PubChem Substance ID: 24724524
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• optical activity: [α]/D 26.0 to 36.0°, c = 0.1 in methanol
• color: pale yellow, oil
• solubility: DMSO: freely soluble; methanol: soluble
• originator: Johnson & Johnson
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O)CCc2ccccc2
• InChI: 1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1
• InChI key: HNPFPERDNWXAGS-NFVOFSAMSA-N
• Gene Information: mouse ... Ptgfr(19220)

Description

Biochem/physiol Actions

Potent, selective FP prostanoid receptor agonist, F-series prostaglandin analog. 200 times as potent as isopropyl ester form.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Store tightly sealed, under desiccant.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves