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Key Documents

D8016

Sigma-Aldrich

Sodium 2,3-dimercaptopropanesulfonate monohydrate

95%

Synonym(s):

2,3-Dimercaptopropanesulfonic acid sodium salt monohydrate, DMPS

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About This Item

Linear Formula:
HSCH2CH(SH)CH2SO3Na · H2O
CAS Number:
Molecular Weight:
228.29
Beilstein:
3734863
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

zwitterionic

Quality Level

Assay

95%

form

powder

mol wt

228.29 g/mol

mp

215 °C (dec.)

storage temp.

2-8°C

SMILES string

O.[Na+].[O-]S(=O)(=O)CC(S)CS

InChI

1S/C3H8O3S3.Na.H2O/c4-9(5,6)2-3(8)1-7;;/h3,7-8H,1-2H2,(H,4,5,6);;1H2/q;+1;/p-1

InChI key

XMUHNMQFDVIWGU-UHFFFAOYSA-M

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General description

Sodium 2,3-dimercaptopropanesulfonate monohydrate is a chelating agent for heavy metals.

Application

Sodium 2,3-dimercaptopropanesulfonate monohydrate has been used in a study to assess its use as an antidote against non-metallic pesticides as nereistoxin insecticides. It has also been noted in a review of existing chelating agents for the treatment of heavy metals and metalloid intoxication.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Santiago Iglesia-Turiño et al.
Plant physiology, 142(2), 742-749 (2006-08-22)
The mercury (Hg) accumulation mechanism was studied in rape (Brassica napus) plants grown under a Hg concentration gradient (0 microm-1,000 microm). Hg mainly accumulated in roots. Therefore, the presence of phytochelatins (PCs) was studied in the roots of the plants.
Swaran J S Flora et al.
International journal of environmental research and public health, 7(7), 2745-2788 (2010-08-19)
Chelation therapy is the preferred medical treatment for reducing the toxic effects of metals. Chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or
Sodium dimercaptopropane sulfonate as antidote against non-metallic pesticides
Chen, Z., et al.
Acta Pharmacologica Sinica, 25, 534-534 (2001)
Holger A Scheidt et al.
Biophysical journal, 109(3), 586-594 (2015-08-06)
Many proteins are anchored to lipid bilayer membranes through a combination of hydrophobic and electrostatic interactions. In the case of the membrane-bound nonreceptor tyrosine kinase Src from Rous sarcoma virus, these interactions are mediated by an N-terminal myristoyl chain and
Christy C Bridges et al.
Toxicology and applied pharmacology, 285(2), 110-117 (2015-04-15)
Secretion of inorganic mercury (Hg(2+)) from proximal tubular cells into the tubular lumen has been shown to involve the multidrug resistance-associated protein 2 (Mrp2). Considering similarities in localization and substrate specificity between Mrp2 and the breast cancer resistance protein (Bcrp)

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