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Key Documents

C8536

Sigma-Aldrich

Z-Ala-Arg-Arg 4-methoxy-β-naphthylamide acetate salt

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About This Item

Empirical Formula (Hill Notation):
C34H46N10O6
CAS Number:
Molecular Weight:
690.79
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32

Assay

≥98% (TLC)

Quality Level

form

powder

solubility

ethanol: 10 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

Cl.CC(NC(=O)OCc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)Nc2ccc3ccccc3c2

InChI

1S/C33H44N10O5.ClH/c1-21(40-33(47)48-20-22-9-3-2-4-10-22)28(44)42-27(14-8-18-39-32(36)37)30(46)43-26(13-7-17-38-31(34)35)29(45)41-25-16-15-23-11-5-6-12-24(23)19-25;/h2-6,9-12,15-16,19,21,26-27H,7-8,13-14,17-18,20H2,1H3,(H,40,47)(H,41,45)(H,42,44)(H,43,46)(H4,34,35,38)(H4,36,37,39);1H

InChI key

SRSBQDNWDTXDRD-UHFFFAOYSA-N

Gene Information

human ... CTSB(1508)
mouse ... CTSB(13030)
rat ... CTSB(64529)

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Amino Acid Sequence

Z-Ala-Arg-Arg-MNA

Substrates

Substrate for cathepsin B

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Separation of a new alpha-N-benzoylarginine-beta-naphthylamide hydrolase from cathepsin B1. Purification, characterization, and properties of both enzymes from rabbit lung.
H Singh et al.
The Journal of biological chemistry, 253(12), 4319-4326 (1978-06-25)
Mahdieh Golizadeh et al.
Pest management science, 78(9), 3788-3794 (2022-01-28)
The use of pest-resistant or less susceptible plant varieties is of great importance for integrated pest management programs. This study was conducted to evaluate the resistance of seven potato cultivars to a major pest, namely the Colorado potato beetle (CPB)

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