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Merck

C5929

Sigma-Aldrich

Calcium carbonate

BioReagent, suitable for insect cell culture, ≥99.0%

Synonym(s):

Limestone, calcite, calofort u, chalk, marble

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About This Item

Linear Formula:
CaCO3
CAS Number:
Molecular Weight:
100.09
Beilstein:
8008338
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.71

Pricing and availability is not currently available.

product line

BioReagent

Quality Level

Assay

≥99.0%

form

powder

technique(s)

cell culture | insect: suitable

solubility

H2O: soluble (10 g + 20 mL of HCl, dilute to 150 mL with H2O)

density

2.93 g/mL at 25 °C (lit.)

SMILES string

[Ca++].[O-]C([O-])=O

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

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General description

Calcium carbonate (CaCO3) is a ternary ionic compound[1] formed by carbon, oxygen, and calcium. It is one of the most common minerals found in rocks worldwide.[2] It aids in studying the process of biomineralization, where it participates in the formation of various mineral structures including marine sediments,[3] shells of marine organisms, snails, coal balls, pearls, and eggshells.[2] CaCO3 exists in different mineral forms such as calcite, aragonite, and vaterite.[4]

Application

Calcium carbonate buffer has been used as a component of alginate solution for tissue culture[5], and for preparing conductive alginate-coated electrodes.[6] It has also been used in the preparation of alginate hydrogel for drug delivery.[7]

Biochem/physiol Actions

Calcium carbonate aids in bone formation and mineralization.[8] It is often used as an antacid due to its potent alkalizing properties.[9] Calcium carbonate has good biocompatibility, porous structure, large surface area, and high loading capacity. These properties of calcium carbonate make it favorable to use as a drug delivery system.[10] In addition, the lower solubility of calcium carbonate (CaCO3) makes it effective in reducing the gelation rate and prolonging the working time for alginate gels. Therefore, it is widely used in the preparation of alginate solution.[11]

Features and Benefits

  • BioReagent grade.
  • High level of assay ( ≥99.0%), indicating its purity.
  • Designed for insect cell culture applications.

Storage Class Code

13 - Non Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Fei Wang et al.
Environmental science & technology, 49(9), 5672-5680 (2015-04-09)
The mineralization of perfluorinated alkyl substances (PFASs) by calcium compounds during the waste thermal treatment was systemically studied. Different calcium compounds showed different mineralization efficiencies of PFASs during the thermal process, owing to the different reaction mechanisms. Calcium hydroxide was
M Azizur Rahman et al.
PloS one, 8(3), e58781-e58781 (2013-03-26)
An organic matrix consisting of a protein-polysaccharide complex is generally accepted as an important medium for the calcification process. While the role this "calcified organic matrix" plays in the calcification process has long been appreciated, the complex mixture of proteins
Jane A Cauley et al.
Journal of women's health (2002), 22(11), 915-929 (2013-10-18)
Clinical outcomes of the Women's Health Initiative (WHI) calcium plus vitamin D supplementation trial have been reported during 7.0 years of active intervention. We now report outcomes 4.9 years after the intervention stopped and cumulative findings. Postmenopausal women (N=36,282) were
Sophie A Jamal et al.
Lancet (London, England), 382(9900), 1268-1277 (2013-07-23)
Phosphate binders (calcium-based and calcium-free) are recommended to lower serum phosphate and prevent hyperphosphataemia in patients with chronic kidney disease, but their effects on mortality and cardiovascular outcomes are unknown. We aimed to update our meta-analysis on the effect of
Ling Li et al.
Nature materials, 13(5), 501-507 (2014-04-01)
Hierarchical composite materials design in biological exoskeletons achieves penetration resistance through a variety of energy-dissipating mechanisms while simultaneously balancing the need for damage localization to avoid compromising the mechanical integrity of the entire structure and to maintain multi-hit capability. Here

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