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Sigma-Aldrich

Sodium hydroxide solution

BioUltra, for molecular biology, 10 M in H2O

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About This Item

Linear Formula:
NaOH
CAS Number:
1310-73-2
Molecular Weight:
40.00
MDL number:
MFCD00003548
UNSPSC Code:
12352316
PubChem Substance ID:
57652395
NACRES:
NA.26

grade

for molecular biology

Quality Level

200

vapor pressure

3 mmHg ( 37 °C)

product line

BioUltra

form

liquid

concentration

10 M in H2O
9500-10500 mmol/L (titration, acidimetric)

technique(s)

ELISA: suitable
immunofluorescence: suitable
western blot: suitable

impurities

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected

pH

14

bp

105-140 °C

mp

-12 - -10 °C (10 - 50 °F)

solubility

water: soluble

density

1.320-1.340 g/cm3

cation traces

Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤100 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

neat

UV absorption

λ: 260 nm Amax: ≤0.08
λ: 280 nm Amax: ≤0.05

SMILES string

[OH-].[Na+]

suitability

suitable for Western blot
suitable for molecular biology

application(s)

agriculture
life science and biopharma

InChI

1S/Na.H2O/h;1H2/q+1;/p-1

InChI key

HEMHJVSKTPXQMS-UHFFFAOYSA-M

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General description

Sodium hydroxide (NaOH) is an inorganic, white solid compound, which is found as pellets, flakes, and granules. This highly caustic metallic base and alkali can readily absorb moisture and carbon dioxide in the air. NaOH is deliquescent and soluble in ethanol, water, and methanol.

Application

Sodium hydroxide solution has been used:
  • to prepare reagent A (0.1 M NaOH) for the pH inactivation of endogenous L-lactate by L-lactate dehydrogenase (L-LDH)
  • as a component of fresh alkaline melting solution for the denaturation of the antisense strand
  • to prepare Type-I collagen hydrogels for microfluidic device fabrication

Biochem/physiol Actions

Sodium hydroxide (NaOH) is used in various industries, including textiles, drinking water, soaps, and detergents, pulp and paper manufacturing, and as a drain cleaner.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

comparable product

Product No.
Description
Pricing

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rikke Wehner Rasmussen et al.
Scandinavian journal of clinical and laboratory investigation, 81(4), 312-317 (2021-04-22)
Intestinal infarction is the fast-evolving endpoint of impaired blood perfusion to an intestinal segment which may have fatal outcome. Early diagnosis and treatment within 6 h reduce mortality. Currently, d-lactate is a promising biomarker, however, not available in the acute clinical
Xin Cui et al.
Biomaterials, 161, 164-178 (2018-02-09)
Glioblastoma (GBM) is the most lethal primary adult brain tumor and its pathology is hallmarked by distorted neovascularization, diffuse tumor-associated macrophage infiltration, and potent immunosuppression. Reconstituting organotypic tumor angiogenesis models with biomimetic cell heterogeneity and interactions, pro-/anti-inflammatory milieu and extracellular
Konstantinos A Polyzos et al.
Cardiovascular research, 106(2), 295-302 (2015-03-10)
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and accumulation of low-density lipoprotein in the artery, leading to maladaptive response of cells from the immune system and vessel wall. Strong evidence implicates indoleamine 2,3-dioxygenase (IDO), the
C Berger et al.
Human reproduction (Oxford, England), 30(4), 800-811 (2015-03-06)
Does ulipristal acetate (UPA) used for emergency contraception (EC) interfere with the human embryo implantation process? UPA, at the dosage used for EC, does not affect human embryo implantation process, in vitro. A single pre-ovulatory dose of UPA (30 mg)
Richard J Travers et al.
Blood, 124(22), 3183-3190 (2014-09-10)
Polyphosphate (polyP) is secreted by activated platelets and has been shown to contribute to thrombosis, suggesting that it could be a novel antithrombotic target. Previously reported polyP inhibitors based on polycationic substances, such as polyethylenimine, polyamidoamine dendrimers, and polymyxin B
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