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PHR1215

Supelco

Lactic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

DL-Lactic acid, 2-Hydroxypropionic acid

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About This Item

Linear Formula:
CH3CH(OH)COOH
CAS Number:
50-21-5
Molecular Weight:
90.08
Beilstein:
1209341
EC Number:
200-018-0
MDL number:
MFCD00004520
UNSPSC Code:
41116107
PubChem Substance ID:
329823222
E Number:
E270
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to USP 1356734

API family

lactic acid

form

liquid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.425 (lit.)

bp

122 °C/15 mmHg (lit.)

density

1.209 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

CC(O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

InChI key

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

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General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Quantitative analysis of four short-chain fatty acids and lactic acids by high-performance liquid chromatography (HPLC) combined with a UV detector from the supernatant of bacterial cultures
  • Spectrophotometric determination of lactic acid at 390 nm in biological cultural and dairy products

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0299 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Supplementary Hazards

EUH071

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD2342
LRAD0398
LRAC0299
LRAD0398
LRAC8050

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Spectrophotometric determination of lactic acid
Borshchevskaya LN, et al.
Journal of Analytical Chemistry, 71, 755-758 (2016)
Oystein Sylta et al.
International journal of sports physiology and performance, 9(1), 100-107 (2014-01-11)
The authors directly compared 3 frequently used methods of heart-rate-based training-intensity-distribution (TID) quantification in a large sample of training sessions performed by elite endurance athletes. Twenty-nine elite cross-country skiers (16 male, 13 female; 25 ± 4 y; 70 ± 11
Paula Gaspar et al.
Biotechnology advances, 31(6), 764-788 (2013-04-10)
The lactic acid bacteria (LAB) are a functionally related group of low-GC Gram-positive bacteria known essentially for their roles in bioprocessing of foods and animal feeds. Due to extensive industrial use and enormous economical value, LAB have been intensively studied
Eileen F O' Shea et al.
Current opinion in biotechnology, 24(2), 130-134 (2013-01-23)
Lactic acid bacteria (LAB) produce a wide variety of antimicrobial peptides (bacteriocins) which contribute to the safety and preservation of fermented foods. This review discusses strategies that have been or could be employed to further enhance the commercial application of
Jan Martinussen et al.
Current opinion in biotechnology, 24(2), 124-129 (2012-12-26)
The ability of lactic acid bacteria to produce lactic acid from various sugars plays an important role in food fermentations. Lactic acid is derived from pyruvate, the end product of glycolysis and thus a fast lactic acid production rate requires
View All Related Papers

Protocols

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Separation of DL-Lactic acid, ~90% (T)

HPLC Analysis of Organic Acids Commonly Found in Wine and Beer on TSKgel® OApak-P and OApak-A

Separation of Pyruvic acid, United States Pharmacopeia (USP) Reference Standard; Tartaric acid, United States Pharmacopeia (USP) Reference Standard; Citric acid, United States Pharmacopeia (USP) Reference Standard; Malic acid, United States Pharmacopeia (USP) Reference Standard; L-Pyroglutamic acid, ≥99.0% (T); Lactic acid, United States Pharmacopeia (USP) Reference Standard; Acetic acid, ≥99.99% trace metals basis; Succinic acid, United States Pharmacopeia (USP) Reference Standard

Chromatograms

application for HPLCapplication for HPLC

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