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80342

Supelco

β-Boswellic acid

analytical standard

Synonym(s):

(3α,4β)-3-Hydroxyurs-12-en-23-oic acid, 3α-Hydroxyurs-12-en-24-oic acid

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About This Item

Empirical Formula (Hill Notation):
C30H48O3
CAS Number:
631-69-6
Molecular Weight:
456.70
MDL number:
MFCD04039448
UNSPSC Code:
85151701
PubChem Substance ID:
329768805
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)[C@@](C)([C@@H]5CC[C@@]34C)C(O)=O)[C@@H]2[C@H]1C

InChI

1S/C30H48O3/c1-18-10-13-26(3)16-17-28(5)20(24(26)19(18)2)8-9-21-27(4)14-12-23(31)30(7,25(32)33)22(27)11-15-29(21,28)6/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21-,22-,23-,24+,26-,27-,28-,29-,30-/m1/s1

InChI key

NBGQZFQREPIKMG-PONOSELZSA-N

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General description

β-Boswellic acid is a naturally occurring pentacyclic triterpene, which can show pharmacological properties like antitumor, anticarcinogenic and antihyperlipidemic activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG9870
BCCD6902
BCBX4705
BCBV5120
BCBQ9673V

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Anti-tumor and anti-carcinogenic activities of triterpenoid,\beta-boswellic acid
Huang T-M, et al. et al.
Biofactors, 13, 225- 230 (2000)
Arne Henkel et al.
Biochemical pharmacology, 83(1), 115-121 (2011-10-18)
Lipophilic extracts of gum resins of Boswellia species (BSE) are used in folk medicine to treat various inflammatory disorders and infections. The molecular background of the beneficial pharmacological effects of such extracts is still unclear. Various boswellic acids (BAs) have
Masanobu Takahashi et al.
Carcinogenesis, 33(12), 2441-2449 (2012-09-18)
Colorectal cancer (CRC) is a complex disease with genetic and epigenetic alterations in many key oncogenes and tumor suppressor genes. The active principle of a gum resin from Boswellia serrata, 3-acetyl-11-keto-β-boswellic acid (AKBA), has recently gained attention as a chemopreventive
Amrita Sharma et al.
Drug delivery, 17(8), 587-595 (2010-07-14)
Boswellic acids (BAs) are isolated from oleo gum resin of Boswellia serrata and are reported to be effective as anti-inflammatory, hypolipidemic, immunomodulatory, and anti-tumor. Pharmacokinetic studies of boswellic acid reveal its poor absorption through the intestine. The objective of the
Kathleen Gerbeth et al.
Journal of pharmaceutical and biomedical analysis, 56(5), 998-1005 (2011-08-23)
Until now, dexamethasone is the medication of choice to reduce peritumoral edema associated with primary and secondary brain tumors. Because of the severe side effects accompanying such a treatment the interest in alternative agents that may be co-administered with glucocorticoids
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