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Sulfadimethoxine-d6

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12D6H8N4O4S
CAS Number:
Molecular Weight:
316.37
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

mass shift

M+6

SMILES string

[2H]C([2H])([2H])Oc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC([2H])([2H])[2H])n1

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)/i1D3,2D3

InChI key

ZZORFUFYDOWNEF-WFGJKAKNSA-N

General description

Sulfadimethoxine-d6 is an isotopically labeled compound of sulfonamide antibiotics. It is typically utilized as an analytical standard in chromatographic determinations.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadoxine-d6 may be used as an analytical standard for the determination of various sulfonamides in:
  • Wastewater samples by ultra-performance liquid chromatography-triple quadrupole-linear ion trap mass spectrometer (UPLC-QqLit-MS).
  • Fish samples as well as soil, sludge and manure samples by LC with tandem mass spectrometry (MS/MS).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Run Tian et al.
Environmental pollution (Barking, Essex : 1987), 247, 1134-1142 (2019-03-03)
Antibiotics are introduced into agricultural fields by the application of manure or biosolids, or via irrigation using reclaimed wastewater. Antibiotics can enter the terrestrial food chains through plant uptake, which forms an alternative pathway for human exposure to antibiotics. However
Multiresidue antimicrobial determination in Nile tilapia (Oreochromis Niloticus) cage farming by liquid chromatography tandem mass spectrometry.
Monteiro SH, et al.
Aquaculture (Amsterdam, Netherlands), 447, 37-43 (2015)
Simultaneous extraction of four classes of antibiotics in soil, manure and sewage sludge and analysis by liquid chromatography-tandem mass spectrometry with the isotope-labelled internal standard method.
Huang Y, et al.
Analytical Methods : Advancing Methods and Applications, 5(15), 3721-3731 (2013)
Laura Micheli et al.
Nutrients, 12(6) (2020-06-04)
Current pharmacological therapies for the management of chronic articular diseases are far from being satisfactory, so new strategies need to be investigated. We tested the intra-articular pain relieving properties of a system of molecules from a characterized Centella asiatica extract
Analysis of multiclass antibiotic residues in urban wastewater in Tunisia.
Harrabi M, et al.
Environmental Nanotechnology, Monitoring & Management, 10, 163-170 (2018)

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