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03880590

Luteolin

primary reference standard

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
Molecular Weight:
286.24
Beilstein:
292084
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

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grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

mp

~330 °C (lit.)

application(s)

food and beverages

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

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This Item
PHL89245L9283440025
Luteolin ≥98% (TLC), powder

L9283

Luteolin

Luteolin An antioxidant flavonoid and a free radical scavenger.

440025

Luteolin

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

manufacturer/tradename

HWI

manufacturer/tradename

PhytoLab

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

mp

~330 °C (lit.)

mp

~330 °C (lit.)

mp

~330 °C (lit.)

mp

-

application(s)

food and beverages

application(s)

-

application(s)

-

application(s)

-

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Standard in the analysis of herbal medicinal products

Other Notes

This compound is commonly found in plants of the genus: achillea

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Lien Verschooten et al.
    PloS one, 7(10), e48264-e48264 (2012-10-31)
    Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma
    Poyil Pratheeshkumar et al.
    PloS one, 7(12), e52279-e52279 (2013-01-10)
    Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid found in fruits and vegetables. We studied the antiangiogenic activity of luteolin using in vitro
    Theoharis C Theoharides et al.
    Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
    Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
    Yong Lin et al.
    Current cancer drug targets, 8(7), 634-646 (2008-11-11)
    Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
    Benguo Liu et al.
    Food chemistry, 141(2), 900-906 (2013-06-26)
    The formation of supramolecular inclusion complexes between luteolin and five cyclodextrins namely β-cyclodextrin (β-CD), methyl-β-cyclodextrin (M-β-CD), hydroxyethyl-β-cyclodextrin (HE-β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD) and glucosyl-β-cyclodextrin (G-β-CD) was investigated. Results from phase-solubility studies showed that luteolin formed 1:1 stoichiometric inclusion complexes with these cyclodextrins

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