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Key Documents

MAB5296

Sigma-Aldrich

Anti-Oxytocin Antibody, clone 4G11

ascites fluid, clone 4G11, Chemicon®

Synonym(s):

Anti-OT, Anti-OT-NPI, Anti-OXT-NPI

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4G11, monoclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG1

NCBI accession no.

NM_000915.2

UniProt accession no.

P01178

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... OXTR(5021)

Specificity

Recognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.

Immunogen

Oxytocin conjugated to thyroglobulin.

Application

Immunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.

ELISA: 1:1,000,000

Optimal working dilutions must be determined by the end user.
This Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Neuroanatomical Evidence for a Role of Central Melanocortin-4 Receptors and Oxytocin in the Efferent Control of the Rodent Clitoris and Vagina.
Gelez H, Poirier S, Facchinetti P, Allers KA, Wayman C, Alexandre L, Giuliano F
Journal of Sexual Medicine null
Mariela Mitre et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(8), 2517-2535 (2016-02-26)
Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent-infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these behaviors, but it is unknown precisely when and where oxytocin receptors
Neuroanatomical evidence for reciprocal regulation of the corticotrophin-releasing factor and oxytocin systems in the hypothalamus and the bed nucleus of the stria terminalis of the rat: Implications for balancing stress and affect.
Dabrowska J, Hazra R, Ahern TH, Guo JD, McDonald AJ, Mascagni F, Muller JF, Young LJ, Rainnie DG
Psychoneuroendocrinology null
Beacon immunoreactivity in the rat hypothalamus.
Y K Ng, G C Brailoiu, S L Dun, E A Ling, J Yang, J K Chang, N J Dun
Journal of Neuroscience Research null
Amy S Kohtz et al.
Psychopharmacology, 235(7), 2051-2063 (2018-04-20)
Initial drug abstinence (modeled here as Extinction Day 1, ED1) is a critical time point in the progression of addiction that is strongly influenced by stress and sex. ED1 induces corticosterone release in both sexes, and cocaine-seeking during ED1 can
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