8.52155

Fmoc-D-Glu(OtBu)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonym(s): Fmoc-D-Glu(OtBu)-OH, N-α-Fmoc-D-glutamic acid γ-t.-butyl ester
• Empirical Formula (Hill Notation): C₂₄H₂₇NO₆
• CAS Number: 104091-08-9
• Molecular Weight: 425.47
• MDL number: MFCD00077055
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• product name: Fmoc-D-Glu(OtBu)-OH, Novabiochem^®
• Quality Level: 200
• product line: Novabiochem^®
• Assay: ≥92.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 80-95 °C
• application(s): peptide synthesis
• functional group: carboxylic acid
• storage temp.: 2-30°C
• InChI: 1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m1/s1
• InChI key: OTKXCALUHMPIGM-HXUWFJFHSA-N

Description

General description

Standard building block of introduction of D-glutamic acid amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-13-1051

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 92.0 %
Water (K. F.): ≤ 6.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable