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850481C

Avanti

16:0-18:0 (9-10BR) PC

1-palmitoyl-2-(9,10-dibromo)stearoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

1-hexadecanoyl-2-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C42H82NO8PBr2
CAS Number:
Molecular Weight:
919.88
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (850481C-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850481C

concentration

10 mg/mL (850481C-10mg)

shipped in

dry ice

storage temp.

−20°C

General description

16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) is a brominated phosphatidylcholine lipid. This lipid is stable for one year.

Application

16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) has been used in large unilamellar vesicles (LUVs) and small unilamellar vesicles (SUVs) for fluorescence quenching. It has also been used to prepare large unilamellar vesicles (LUV) for liposome co-sedimentation assay. It may be used as a component in large unilamellar liposomes for parallax analysis and in lipid vesicle preparation for tryptophan (Trp) penetration depth experiments/bromine quenching experiments.

Biochem/physiol Actions

16:0-18:0 (9-10BR) PC (1-palmitoyl-2-(9,10-dibromo) stearoyl-sn-glycero-3-phosphocholine) can act as a deep quencher.

Packaging

5 mL Clear Glass Sealed Ampule (850481C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mutations in glucocerebrosidase (GCase), the enzyme deficient in Gaucher disease, are a common genetic risk factor for the development of Parkinson disease and related disorders, implicating the role of this lysosomal hydrolase in the disease etiology. A specific physical interaction
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Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed. Single-domain antibodies (VHH) have been examined as a countermeasure for BoNT because of their high stability and

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