810132P
Avanti
18:1-06:0 NBD PC
Avanti Research™ - A Croda Brand
Synonym(s):
1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C38H64N5O11P
CAS Number:
Molecular Weight:
797.92
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810132P-1mg)
pkg of 5 × 1 mg (810132P-5mg)
pkg of 5 × 2 mg (810132P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylcholine (PC) is a prime metabolite of glycerolipid metabolism in eukaryotes. It is a vital component of the mucosal layer of the colon and a strong bilayer-forming lipid. NBD PC has 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) moiety attached to phosphatidylcholine.
Application
18:1-06:0 NBD PC is suitable:
- for the generation of giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy
- for labeling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy
- for the preparation of phospholipid-coated beads
Biochem/physiol Actions
7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is used as a fluorescent probe in biological membranes to study the cellular processes.
Packaging
5 mL Amber Glass Screw Cap Vial (810132P-10mg)
5 mL Amber Glass Screw Cap Vial (810132P-1mg)
5 mL Amber Glass Screw Cap Vial (810132P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Chung Park et al.
eLife, 8 (2019-12-04)
During human immunodeficiency virus-1 (HIV-1) infection lymphoid organ follicular dendritic cells (FDCs) serve as a reservoir for infectious virus and an obstacle to curative therapies. Here, we identify a subset of lymphoid organ sinus lining macrophage (SMs) that provide a
Johan Tornmalm et al.
Scientific reports, 9(1), 18133-18133 (2019-12-04)
Protein-lipid interactions in cellular membranes modulate central cellular functions, are often transient in character, but occur too intermittently to be readily observable. We introduce transient state imaging (TRAST), combining sensitive fluorescence detection of fluorophore markers with monitoring of their dark
Yuta Ryoden et al.
Journal of immunology (Baltimore, Md. : 1950), 204(3), 559-568 (2019-12-22)
In response to extracellular ATP, the purinergic receptor P2X7 mediates various biological processes, including phosphatidylserine (PtdSer) exposure, phospholipid scrambling, dye uptake, ion transport, and IL-1β production. A genome-wide CRISPR screen for molecules responsible for ATP-induced PtdSer exposure identified a transmembrane
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