QBD10288

m-dPEG^®₁₂-amine

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₂₅H₅₃NO₁₂
• CAS Number: 32130-27-1
• Molecular Weight: 559.69
• MDL number: MFCD11041151
• UNSPSC Code: 12352116
• PubChem Substance ID: 329823908
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: carboxyl reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Description

Features and Benefits

m-dPEG^®₁₂-amine provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. The number after the dPEG^® is the specific number of repeat units in the linear chain. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₁₂-amine reacts with carboxylic acids and active esters.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable