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M1641

Sigma-Aldrich

Methoxyphenamine hydrochloride

≥99%

Synonym(s):

2-Methoxy-N,α-dimethylbenzeneethanamine hydrochloride, NSC 65644

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About This Item

Empirical Formula (Hill Notation):
C11H17NO · HCl
CAS Number:
Molecular Weight:
215.72
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99%

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

SMILES string

Cl.CNC(C)Cc1ccccc1OC

InChI

1S/C11H17NO.ClH/c1-9(12-2)8-10-6-4-5-7-11(10)13-3;/h4-7,9,12H,8H2,1-3H3;1H

InChI key

FGSJNNQVSUVTPW-UHFFFAOYSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hajime Miyaguchi et al.
Journal of chromatography. A, 1129(1), 105-110 (2006-07-29)
A microchip-based liquid-liquid extraction for the gas chromatography analysis of urine for amphetamine-type stimulants has been developed. Partially modified microchannels with the capillarity restricted modification (CARM) method were employed for stabilizing the interface consisting of 1-chlorobutane and alkalized urine. Reliability
S Geertsen et al.
Xenobiotica; the fate of foreign compounds in biological systems, 25(9), 895-906 (1995-09-01)
1. Control and P4502D6-transfected human B-lymphoblastoid cell lines (cHol and h2D6v2 respectively) were used to study 2D6-mediated metabolism of methoxyphenamine (MPA) and 2-methoxyamphetamine (2MA). The main metabolites were products of O-dealkylation and aromatic hydroxylation at the 5-position. In addition, N-desmethyl-methoxyphenamine
N R Srinivas et al.
Journal of chromatography, 487(1), 61-72 (1989-01-27)
Sensitive and enantioselective gas chromatographic assays have been developed and applied to the quantitation in human urine of the enantiomers of methoxyphenamine and its three primary oxidative metabolites, namely, N-desmethylmethoxyphenamine, O-desmethylmethoxyphenamine and 5-hydroxymethoxyphenamine. The separation of the various analytes was
G Muralidharan et al.
Xenobiotica; the fate of foreign compounds in biological systems, 21(11), 1441-1450 (1991-11-01)
1. Lewis rats (n = 7 or 8) were dosed with methoxyphenamine with and without prior administration of various doses of either quinine or its diastereomer quinidine. Methoxyphenamine and its N-desmethyl, O-desmethyl and aromatic 5-hydroxy metabolites were quantified in 0-24
Y Nakahara et al.
Forensic science international, 63(1-3), 109-119 (1993-12-01)
The excretion of methoxyphenamine (MOP) and methamphetamine (MA) into beards has been studied. Six healthy male subjects orally took 50 mg of MOP at a single dose and 7 doses for a successive 7 days. Their beard hairs were collected

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