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Key Documents

L060030

Sigma-Aldrich

Oxidizer

0.1 M, configured for ABI

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About This Item

MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

type

for DNA synthesis

product line

Proligo Reagents

form

liquid

shelf life

365 days

concentration

22.9-27.9 g/L (Iodine content, titration)

color

clear, brownish solution

compatibility

configured for ABI

storage temp.

2-8°C

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General description

Oxidizer solution, containing tetrahydrofuran (THF), pyridine, iodine, and water, is applied to oxidize the chemically unstable trivalent phosphorous triester linkage formed in the coupling reaction to a stable pentavalent phosphate triester. Iodine functions as a mild oxidant and water functions as an oxygen donor.The product is configured for ABI 39X/3400 FormulationFormulation.

Preparation Note

Tetrahyrofurane/Water/Pyridine/Iodine 77/2/21/2.54 (v/v/v/w)

Legal Information

ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system, Respiratory system, Thyroid

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

6.1 °F

Flash Point(C)

-14.4 °C


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