D163708
N,O-Dimethylhydroxylamine hydrochloride
98%
Synonym(s):
N,O-Dimethylhydroxylamine HCl, N-Methoxymethylamine hydrochloride, Methoxymethylamine hydrochloride
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About This Item
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Quality Level
Assay
98%
form
crystals
mp
112-115 °C
SMILES string
Cl[H].CNOC
InChI
1S/C2H7NO.ClH/c1-3-4-2;/h3H,1-2H3;1H
InChI key
USZLCYNVCCDPLQ-UHFFFAOYSA-N
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Application
Reagent for the preparation of Weinreb amides recently used in the synthesis of 2-acyloxazoles from 2-oxazolemagnesium chloride.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The Journal of organic chemistry, 72(15), 5828-5831 (2007-06-26)
Treatment of oxazole or 5-aryl oxazoles with i-PrMgCl smoothly generates the corresponding 2-Grignard reagents, which react with Weinreb amides to provide exclusively 2-acyl oxazole products.
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