ALD00628

6-(Quinolin-2-yl)pyridin-2(1H)-one

≥95%

• Empirical Formula (Hill Notation): C₁₄H₁₀N₂O
• CAS Number: 1006365-14-5
• Molecular Weight: 222.24
• MDL number: MFCD28340284
• UNSPSC Code: 12352100
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95%
• form: powder
• storage temp.: −20°C

Description

Application

This ligand was developed by the Yu lab to enable the Pd-catalyzed dehydrogenation of aliphatic carboxylic acids through a typically challenging activation of the β-methylene C-H bond. This method is chemoselective to carboxylic acids even in the presence of other enolizable functional groups, and may also viably utilize molecular oxygen as the terminal oxidant for the transformation.

Other Notes

Ligand-controlled divergent dehydrogenative reactions of carboxylic acids via C–H activation

A tautomeric ligand enables directed C-H hydroxylation with molecular oxygen

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable