937754
Poly(D,L-lactic-co-glycolic acid)-block-poly(glutamic acid)
PLGA average Mn 25,000, mol wt (PGlu average Mn 5,000), lactide:glycolide 50:50
Synonym(s):
Amphiphilic, Block polymer, Drug delivery, Glutamic acid, PLGA, PLGA-b-PGlu, Poly(glutamic acid), Polyaminoacids
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About This Item
Linear Formula:
[(C3H4O2)a(C2H2O2)b]n O[C5H7NO3]m
UNSPSC Code:
12162002
NACRES:
NA.21
Recommended Products
feed ratio
lactide:glycolide 50:50
Quality Level
mol wt
PLGA average Mn 25,000
(PGlu average Mn 5,000)
color
white to beige, powder
storage temp.
−20°C
Application
This polymer is a amphiphilic diblock copolymer composed of a hydrophobic PLGA block and a hydrophilic poly(glutamic acid) block. PLGA is a biocompatible and biodegradable polymer that has been approved by the FDA and the EMA for biomedical and pharmaceutical applications. Poly(glutamic acid) is biodegradable, non-toxic and non-immunogenic macromolecules. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, for drug delivery applications
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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