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935433

Sigma-Aldrich

Heparin methacrylate (HepMA)

Synonym(s):

3D bioprinting, Bioprinting, HepMA, Heparin, Heparin methacrylate, Hydrogel

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.21

description

Degree of functionalization: 10-30% methacrylation

Quality Level

form

powder or chunks (or fibers)

color

white to off-white

storage temp.

2-8°C

General description

Heparin methacrylate (HepMa) is a functionalized natural polymer that can be used in 3D bioprinting and tissue engineering applications.

Heparin is a naturally occurring linear biopolymer and highly sulfated glycosaminoglycan (GAG). Research has demonstrated that heparin can modulate binding extracellular matrix proteins and sequester growth factors and cytokines, making them useful in 3D applications. The methacrylate-functionalization of heparin allows thermal or photochemical crosslinking via covalent conjugation. Heparins exhibit high anionic charge densities to promote large swelling ratios in water.

Application

Heparin based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug delivery applications.

Features and Benefits

  • Batch control offers reproducible models for preclinical toxicology testing and drug screening
  • Extended shelf-life & stability

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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