935433
Heparin methacrylate (HepMA)
Synonym(s):
3D bioprinting, Bioprinting, HepMA, Heparin, Heparin methacrylate, Hydrogel
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About This Item
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description
Degree of functionalization: 10-30% methacrylation
Quality Level
form
powder or chunks (or fibers)
color
white to off-white
storage temp.
2-8°C
Related Categories
General description
Heparin methacrylate (HepMa) is a functionalized natural polymer that can be used in 3D bioprinting and tissue engineering applications.
Heparin is a naturally occurring linear biopolymer and highly sulfated glycosaminoglycan (GAG). Research has demonstrated that heparin can modulate binding extracellular matrix proteins and sequester growth factors and cytokines, making them useful in 3D applications. The methacrylate-functionalization of heparin allows thermal or photochemical crosslinking via covalent conjugation. Heparins exhibit high anionic charge densities to promote large swelling ratios in water.
Heparin is a naturally occurring linear biopolymer and highly sulfated glycosaminoglycan (GAG). Research has demonstrated that heparin can modulate binding extracellular matrix proteins and sequester growth factors and cytokines, making them useful in 3D applications. The methacrylate-functionalization of heparin allows thermal or photochemical crosslinking via covalent conjugation. Heparins exhibit high anionic charge densities to promote large swelling ratios in water.
Application
Heparin based hydrogels are widely used in tissue engineering, 3D bioprinting, and drug delivery applications.
Features and Benefits
- Batch control offers reproducible models for preclinical toxicology testing and drug screening
- Extended shelf-life & stability
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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