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Key Documents

934100

Sigma-Aldrich

Ovine collagen

maleimide functionalized, low endotoxin

Synonym(s):

CollOvine-PEG2-MAL

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.28

form

lyophilized powder

Quality Level

impurities

Bioburden, none detected
low endotoxin
≤0.1 EU/mg Endotoxin

color

white to off-white

functional group

maleimide

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General description

Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Low endotoxin maleimide functionalized collagen derived from ovine has many biomedical applications and is a great alternative to other naturally derived materials such as those derived from bovine or porcine. Maleimide conjugations are commonly used to generate covalent conjugates with sulfhydryl containing molecules. This thiol-maleimide click chemistry reaction is commonly used for bioconjugation given its reliability, efficiency, selectivity, and preferential chemical reaction at neutral pH. The PEGylated maleimide functionalization provides methods for easy bioconjugation while maintain the advantages of the naturally derived collagen.

Application

  • 3D bioprinting
  • Tissue engineering
  • Drug delivery
  • Regenerative medicine
  • Cell culture, encapsulation, expansion and differentiation

Features and Benefits

  • Certified Disease Free Sheep
  • 93-97% Type I Collagen
  • 3-7% Type III Collagen
  • 99% Purity
  • Prion Free

Legal Information

CollOvine is a trademark of OviGenex LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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