923842

Alginate Aldehyde

35% aldehyde content, medium viscosity

• Synonym(s): Alginate aldehyde, Oxidized alginate
• Linear Formula: (C₆H₇NaO₆)_n(C₆H₃NaO₆)_m
• UNSPSC Code: 12352201
• NACRES: NA.23

Properties

• Quality Level: 100
• description: Degree of functionalization: 30-40%
• form: powder
• sheet resistance: 15.6m Ω/sq (25 mum after curing at 150 Celsius for 5 min on glass)
• color: white to off-white
• suitability: conforms to structure for NMR
• storage temp.: 2-8°C
• SMILES string: CO[C@H]1[C@@H](O)[C@H](O)[C@H](O/C(C=O)=C\C([O-])=O)O[C@@H]1C([O-])=O.OC2[C@H](OC(O)C=O)[C@@H](C([O-])=O)O[C@@H](OC)[C@H]2O

Description

Application

Alginate is an anionic polysaccharide that is widely used in pharmaceutical and biomedical applications due to its non-animal origin, low toxicity, biocompatibility, and biodegradability[1]. Alginate hydrogels are commonly used to fabricate tissue engineering scaffolds[3], bioinks for 3D bioprinting[2][4], and nanocarriers for drug &gene;delivery.

Alginate is commonly crosslinked into a hydrogel via ionic-crosslinking with divalent cations (e.g., Ca²⁺). To prevent matrix degradation, alginate can be functionalized with reactive groups that can be chemically crosslinked, such as aldehydes.[5] Aldehyde- functionalized alginate can be used to prepare hydrogels by reaction with amine groups, such as gelatin through Schiff-base reaction to form a chemical hydrogel. This material can be used in a variety of biomedical applications such as the delivery of drugs, cells, or biomolecules in different tissues, wound healing, and muscle and bone tissue engineering. [6]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable