902934
Allyl-poly(ethylene glycol)
average Mn 5,000, PDI <1.3
Synonym(s):
Allyl-PEG-OH, PEG 5k, PEG allyl, Polyethylene glycol
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form
powder or solid
mol wt
PEG ~5,000 Da
average Mn 5,000
color
off-white to pale yellow
PDI
<1.3
storage temp.
2-8°C
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General description
Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
Application
This heterobifunctional PEG has an allyl functionality on one end and an alcohol on the other. The allyl is commonly used in thiol-ene click chemistry; as well as other ligation reactions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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